We care for the health of your skin
2121 Santa Monica Blvd.​, ​(Garden Level), Santa Monica, CA 90404
Tel: 310-449-5265 - Fax: 562-261-1059
"An ounce of prevention is worth a pound of cure." - Benjamin Franklin
NASA helps Dr. Lee analyze DNA in the breast’s ductal systems, which produce milk and secrete a substance called nipple aspirate fluid.
You are only a click away from the most amazing skin
"An ounce of prevention is worth a pound of cure." - Benjamin Franklin
About
Dr. Delphine Lee, M.D., Ph.D, focuses on the health and wellness of your skin, hair and nails. The skin is the largest and most exposed organ of the body, susceptible to infection, cancer and autoimmunity. As an expert in how the immune system functions, Dr. Lee emphasizes prevention and early diagnosis.
Areas of Special Interest
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​​Autoimmune Diseases (Blistering diseases, Vitiligo, Complicated rashes)
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Melanoma, esp. immune therapy for skin metastases
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Complex Medical Dermatology
Community news
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Dr. Lee and her team published their new study, Primary Cutaneous Melanoma Microbiome Is Associated with Overall Survival and Recurrence in the Journal of Investigative Dermatology, March 2026. Their work provides some insights that bacteria inside melanoma tumors may offer clues about cancer outcomes.
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Dr. Lee and her colleague Dr. Mirjam Schenk published their new study, Agonistic GITR treatment enhances antitumor immune responses and suppresses tumor progression in pancreatic ductal adenocarcinoma in The Journal of Gastroenterology, February, 2026.
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Dr. Lee and her team describe the first report of the breast tissue microbiome in a murine model of breast cancer in Translational Oncology, entitled "Mammary tissue microbiome analysis in PyMT mice reveals Methylobacteria as a commensal organism with potential therapeutic applications” June 2025.
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Dr. Lee lectured on "Randomized Controlled Trials in Vitiligo-what have we learned?" at the 2024 CalDerm Annual Fall Symposium on September 8, 2024.
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Dr. Lee and her colleague Dr. Diaz published their new study, N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma, July 25, 2024.
Clinical
Dr. Lee is the Director of the Dermatological Center for Skin Health with expertise in complicated skin rashes and skin cancer. She treats her private patients at St. John's Health Center in Santa Monica. She is also the Chief of Dermatology and Residency Program Director at Harbor-UCLA Medical Center in Torrance, California.
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Research
​Under Dr. Lee’s direction, investigators on her team at the Lundquist Institute are respected researchers whose expertise extend well beyond cancer, allowing them to draw parallels between the inappropriate immune responses causing diseases: both cancer and non-cancerous. A key focus of her laboratory is to investigate how microbes and other small molecules affect antitumor immune responses and autoimmunity/autoinflammation. Research involves cutting edge basic science and computational techniques to study and manipulate the immune system in melanoma, breast cancer, and other inflammatory skin conditions.